eGFR Calculator (MDRD Formula)
Estimate glomerular filtration rate using the 4-variable MDRD equation for chronic kidney disease staging based on serum creatinine, age, gender, and race.
Results
What is it?
For educational and clinical reference only. Not a substitute for professional medical judgment. Always verify with current clinical guidelines and consult qualified healthcare providers. The MDRD (Modification of Diet in Renal Disease) formula estimates glomerular filtration rate (GFR) from serum creatinine. CKD stages: G1 =90 (normal), G2 60�89 (mildly decreased), G3a 45�59, G3b 30�44, G4 15�29, G5 <15 (kidney failure). Note: MDRD may underestimate GFR at higher levels; CKD-EPI is preferred for eGFR >60.
How to use
Enter the most recent serum creatinine in mg/dL, patient age, biological sex, and race. The MDRD eGFR is calculated automatically. Use IDMS-traceable creatinine assays for accurate results.
Example scenario
A 65-year-old non-Black male with creatinine 1.5 mg/dL: eGFR = 175 � 1.5^(-1.154) � 65^(-0.203) � 1 � 1 � 46 mL/min/1.73m� ? CKD Stage G3a.
Pro tip
MDRD is validated for creatinine-stable CKD patients. Do not use in AKI, pregnancy, extremes of muscle mass (bodybuilders, amputees), or malnutrition. For drug dosing (e.g., renally-cleared antibiotics, DOACs, metformin), use absolute GFR = eGFR � BSA/1.73.