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Morphine Milligram Equivalent (MME) Calculator

Convert opioid doses to morphine milligram equivalents (MME/day) to assess total opioid burden and apply CDC prescribing guideline thresholds.

Conversion factors per CDC 2022 guidelines. Fentanyl: enter �g/hr patch dose.
Number of doses administered per day. Use 1 for extended-release or once-daily formulations.

Results

Total Daily Dose90.0 mg/day
Total Daily MME90.0 MME/day
CDC Risk Flag (0=Normal, 1=Caution =50, 2=High =90)2

📖What is it?

For educational and clinical reference only. Not a substitute for professional medical judgment. Always verify with current clinical guidelines and consult qualified healthcare providers. Morphine Milligram Equivalents (MME) standardize opioid doses to a common unit for assessing total opioid burden. The 2022 CDC Clinical Practice Guideline recommends caution at =50 MME/day and careful evaluation at =90 MME/day due to overdose risk. MME factors vary by source; always verify against current institutional and national guidelines.

🎯How to use

Select the opioid, enter the per-dose amount (mg for oral/parenteral, �g/hr for fentanyl patches), and the number of doses per day. For extended-release formulations (once daily), set doses per day to 1. The total daily MME and CDC risk tier are displayed.

💡Example scenario

Oxycodone IR 10 mg three times daily: totalDailyMg = 10�3 = 30 mg/day. MME = 30�1.5 = 45 MME/day (below 50 threshold). If increased to 15 mg TID: 45 mg � 1.5 = 67.5 MME/day ? Caution tier.

🏆Pro tip

Buprenorphine MME conversion is controversial; the 30� factor is approximate and may not reflect equianalgesic equivalence. Methadone has a complex, non-linear conversion that is NOT included here � always consult a pain or palliative care specialist. Do not use this calculator to make opioid rotation decisions without clinical expertise.